@article {https://doi.org/10.1002/ejoc.202200623, title = {Expeditious Synthesis of a Glycopeptide Library}, journal = {European Journal of Organic Chemistry}, volume = {e202200623}, year = {2022}, note = {[[{"fid":"258861","view_mode":"default","type":"media","attributes":{"height":"228","width":"1000","style":"width: 500px; height: 100px;","alt":"drorr","class":"img-responsive media-element file-default"}}]]}, abstract = {

Short proteoglycan fragments are of great importance for biochemical research. The solid-phase synthesis of such glycopeptides relies on excessive use of glycosylated amino acids, extended reaction times, and additional post-assembly deprotection protocols. We employed high-shear mixing for expedient and equimolar O-glycopeptide assembly. We further developed a stirring-based deprotection on the solid support, thus completing the synthesis of a glycopeptide library in a minimal amount of time and purification hurdles.\ Publisher{\textquoteright}s Version

}, keywords = {deacetylation, Glycopeptides, Glycosylated amino acids, solid-phase synthesis, synthetic methods}, doi = {https://doi.org/10.1002/ejoc.202200623}, author = {Ben Abba Amiel, Dror and Mattan Hurevich} }