Citation:
Bakhatan, Y. ; Ben Abba Amiel, D. ; Sukhran, Y. ; Chan, C. - K. ; Lo, W. - C. ; Lu, P. - W. ; Liao, P. - H. ; Wang, C. - C. ; Hurevich, M. . Translating Solution To Solid Phase Glycosylation Conditions. Chem. Commun. 2022, 58, 11256-11259.
Abstract:
Optimizing glycosylation conditions for automated glycan assembly is highly challenging, demand wasteful use of precious building blocks and rely on nontrivial analyses. We developed a semi-quantitative method for automated optimization of glycosylation temperature that utilized minute quantities of donors and translated those conditions to solid-phase glycan assembly.
Notes:
